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1

GWAS of epigenetic aging rates in blood reveals a critical role for TERT

Lu, Ake T., Xue, Luting, Salfati, Elias L., Chen, Brian H., Ferrucci, Luigi, Levy, Daniel, Joehanes, Roby, Murabito, Joanne M., Kiel, Douglas P., Tsai, Pei-Chien, Yet, Idil, Bell, Jordana T., Mangino,

Journal:

Nature Communications

Year:

2018

Language:

english

File:

PDF, 1.43 MB

english, 2018

2

Gene expression analysis of whole blood, peripheral blood mononuclear cells, and lymphoblastoid cell lines from the Framingham Heart Study

Joehanes, R., Johnson, A. D., Barb, J. J., Raghavachari, N., Liu, P., Woodhouse, K. A., O'Donnell, C. J., Munson, P. J., Levy, D.

Journal:

Physiological Genomics

Year:

2012

Language:

english

File:

PDF, 1.49 MB

english, 2012

3

A Systems Biology Framework Identifies Molecular Underpinnings of Coronary Heart Disease

Huan, T., Zhang, B., Wang, Z., Joehanes, R., Zhu, J., Johnson, A. D., Ying, S., Munson, P. J., Raghavachari, N., Wang, R., Liu, P., Courchesne, P., Hwang, S.-J., Assimes, T. L., McPherson, R., Samani,

Journal:

Arteriosclerosis Thrombosis and Vascular Biology

Year:

2013

Language:

english

File:

PDF, 2.86 MB

english, 2013

4

Epigenome-Wide Association Study of Fasting Blood Lipids in the Genetics of Lipid-Lowering Drugs and Diet Network Study

Irvin, M. R., Zhi, D., Joehanes, R., Mendelson, M., Aslibekyan, S., Claas, S. A., Thibeault, K. S., Patel, N., Day, K., Jones, L. W., Liang, L., Chen, B. H., Yao, C., Tiwari, H. K., Ordovas, J. M., Le

Journal:

Year:

2014

Language:

english

File:

PDF, 2.82 MB

english, 2014

5

Integrative DNA, RNA, and Protein Evidence Connects TREML4 to Coronary Artery Calcification

Sen, Shurjo K., Boelte, Kimberly C., Barb, Jennifer J., Joehanes, Roby, Zhao, XiaoQing, Cheng, Qi, Adams, Lila, Teer, Jamie K., Accame, David S., Chowdhury, Soma, Singh, Larry N., Kavousi, Maryam, Pey

Journal:

The American Journal of Human Genetics

Year:

2014

Language:

english

File:

PDF, 2.25 MB

english, 2014

6

[IEEE Comput. Soc 23rd International Conference on Software Engineering. ICSE 2001 - Toronto, Ont., Canada (12-19 May 2001)] Proceedings of the 23rd International Conference on Software Engineering. ICSE 2001 - Tool-supported program abstraction for finite-state verification

Dwyer, M.B., Hatcliff, J., Joehanes, R., Laubach, S., Pasreanu, C.S., Zheng, R.H., Visser, W.

Year:

2001

Language:

english

File:

PDF, 1.12 MB

english, 2001

7

Sex- and age-interacting eQTLs in human complex diseases

Yao, C., Joehanes, R., Johnson, A. D., Huan, T., Esko, T., Ying, S., Freedman, J. E., Murabito, J., Lunetta, K. L., Metspalu, A., Munson, P. J., Levy, D.

Journal:

Human Molecular Genetics

Year:

2014

Language:

english

File:

PDF, 670 KB

english, 2014

8

Whole blood gene expression and interleukin-6 levels

Lin, Honghuang, Joehanes, Roby, Pilling, Luke C., Dupuis, Josée, Lunetta, Kathryn L., Ying, Sai-Xia, Benjamin, Emelia J., Hernandez, Dena, Singleton, Andrew, Melzer, David, Munson, Peter J., Levy, Dan

Journal:

Year:

2014

Language:

english

File:

PDF, 516 KB

english, 2014

9

Integromic Analysis of Genetic Variation and Gene Expression Identifies Networks for Cardiovascular Disease Phenotypes

Yao, C., Chen, B. H., Joehanes, R., Otlu, B., Zhang, X., Liu, C., Huan, T., Tastan, O., Cupples, L. A., Meigs, J. B., Fox, C. S., Freedman, J. E., Courchesne, P., O'Donnell, C. J., Munson, P. J., Kele

Journal:

Year:

2015

Language:

english

File:

PDF, 4.46 MB

english, 2015

10

A systematic heritability analysis of the human whole blood transcriptome

Huan, Tianxiao, Liu, Chunyu, Joehanes, Roby, Zhang, Xiaoling, Chen, Brian H., Johnson, Andrew D., Yao, Chen, Courchesne, Paul, O’Donnell, Christopher J., Munson, Peter J., Levy, Daniel

Journal:

Year:

2015

Language:

english

File:

PDF, 1.20 MB

english, 2015

11

Dissecting the Roles of MicroRNAs in Coronary Heart Disease via Integrative Genomic Analyses

Huan, T., Rong, J., Tanriverdi, K., Meng, Q., Bhattacharya, A., McManus, D. D., Joehanes, R., Assimes, T. L., McPherson, R., Samani, N. J., Erdmann, J., Schunkert, H., Courchesne, P., Munson, P. J., J

Journal:

Arteriosclerosis Thrombosis and Vascular Biology

Year:

2015

Language:

english

File:

PDF, 605 KB

english, 2015

12

Identification of common genetic variants controlling transcript isoform variation in human whole blood

Zhang, Xiaoling, Joehanes, Roby, Chen, Brian H, Huan, Tianxiao, Ying, Saixia, Munson, Peter J, Johnson, Andrew D, Levy, Daniel, O'Donnell, Christopher J

Journal:

Nature Genetics

Year:

2015

Language:

english

File:

PDF, 835 KB

english, 2015

13

Genome-wide identification of microRNA expression quantitative trait loci

Huan, Tianxiao, Rong, Jian, Liu, Chunyu, Zhang, Xiaoling, Tanriverdi, Kahraman, Joehanes, Roby, Chen, Brian H., Murabito, Joanne M., Yao, Chen, Courchesne, Paul, Munson, Peter J., O’Donnell, Christoph

Journal:

Nature Communications

Year:

2015

Language:

english

File:

PDF, 878 KB

english, 2015

14

Gene Expression Signatures of Coronary Heart Disease

Joehanes, R., Ying, S., Huan, T., Johnson, A. D., Raghavachari, N., Wang, R., Liu, P., Woodhouse, K. A., Sen, S. K., Tanriverdi, K., Courchesne, P., Freedman, J. E., O'Donnell, C. J., Levy, D., Munson

Journal:

Arteriosclerosis Thrombosis and Vascular Biology

Year:

2013

Language:

english

File:

PDF, 3.08 MB

english, 2013

15

QGene 4.0, an extensible Java QTL-analysis platform

Joehanes, R., Nelson, J. C.

Journal:

Year:

2008

Language:

english

File:

PDF, 62 KB

english, 2008

16

A Meta-analysis of Gene Expression Signatures of Blood Pressure and Hypertension

Huan, Tianxiao, Esko, Tõnu, Peters, Marjolein J., Pilling, Luke C., Schramm, Katharina, Schurmann, Claudia, Chen, Brian H., Liu, Chunyu, Joehanes, Roby, Johnson, Andrew D., Yao, Chen, Ying, Sai-xia, C

Journal:

Year:

2015

Language:

english

File:

PDF, 1.31 MB

english, 2015

17

Gene expression markers of age-related inflammation in two human cohorts

Pilling, Luke C., Joehanes, Roby, Melzer, David, Harries, Lorna W., Henley, William, Dupuis, Josée, Lin, Honghuang, Mitchell, Marcus, Hernandez, Dena, Ying, Sai-Xia, Lunetta, Kathryn L., Benjamin, Eme

Journal:

Experimental Gerontology

Year:

2015

Language:

english

File:

PDF, 1.08 MB

english, 2015

18

Integrative network analysis reveals molecular mechanisms of blood pressure regulation

Huan, T., Meng, Q., Saleh, M. A., Norlander, A. E., Joehanes, R., Zhu, J., Chen, B. H., Zhang, B., Johnson, A. D., Ying, S., Courchesne, P., Raghavachari, N., Wang, R., Liu, P., O'Donnell, C. J., Vasa

Journal:

Molecular Systems Biology

Year:

2015

Language:

english

File:

PDF, 1.12 MB

english, 2015

19

The transcriptional landscape of age in human peripheral blood

Peters, Marjolein J., Joehanes, Roby, Pilling, Luke C., Schurmann, Claudia, Conneely, Karen N., Powell, Joseph, Reinmaa, Eva, Sutphin, George L., Zhernakova, Alexandra, Schramm, Katharina, Wilson, Yan

Journal:

Nature Communications

Year:

2015

Language:

english

File:

PDF, 1.73 MB

english, 2015

20

Gene transcripts associated with muscle strength: a CHARGE meta-analysis of 7,781 persons

Pilling, L. C., Joehanes, R., Kacprowski, T., Peters, M., Jansen, R., Karasik, D., Kiel, D. P., Harries, L. W., Teumer, A., Powell, J., Levy, D., Lin, H., Lunetta, K., Munson, P., Bandinelli, S., Henl

Journal:

Physiological Genomics

Year:

2016

Language:

english

File:

PDF, 526 KB

english, 2016

21

[Offshore Technology Conference Offshore Technology Conference-Asia - Kuala Lumpur, Malaysia (2014-03-25)] Offshore Technology Conference-Asia - Jack Up Suitability for South China Sea Sites

Nancy, Chan, B Rohani, Muhammad Joehan, Bt M Hazizy, Rozana, B Abd Rahman, Azam, Jalil, Azri B A

Language:

english

File:

PDF, 899 KB

english

22

[International Petroleum Technology Conference International Petroleum Technology Conference - Kuala Lumpur, Malaysia (2014-12-10)] International Petroleum Technology Conference - Jack-Up Suitability from a Risk Assessment Perspective

Rohani, Muhammad Joehan, M. W. Ismail, Wan M, Sha'ari, Fatimah Az-Zahra', A Jalil, Azri

Language:

english

File:

PDF, 2.68 MB

english

23

A Whole-Blood Transcriptome Meta-Analysis Identifies Gene Expression Signatures of Cigarette Smoking

Huan, Tianxiao, Joehanes, Roby, Schurmann, Claudia, Schramm, Katharina, Pilling, Luke C., Peters, Marjolein J., Mägi, Reedik, DeMeo, Dawn, O'Connor, George T, Ferrucci, Luigi, Teumer, Alexander, Homut

Journal:

Human Molecular Genetics

Year:

2016

Language:

english

File:

PDF, 447 KB

english, 2016

24

DNA methylation signatures of chronic low-grade inflammation are associated with complex diseases

Ligthart, Symen, Marzi, Carola, Aslibekyan, Stella, Mendelson, Michael M., Conneely, Karen N., Tanaka, Toshiko, Colicino, Elena, Waite, Lindsay L., Joehanes, Roby, Guan, Weihua, Brody, Jennifer A., El

Journal:

Year:

2016

Language:

english

File:

PDF, 972 KB

english, 2016

25

Whole Blood Gene Expression and Atrial Fibrillation: The Framingham Heart Study

Lin, Honghuang, Yin, Xiaoyan, Lunetta, Kathryn L., Dupuis, Josée, McManus, David D., Lubitz, Steven A., Magnani, Jared W., Joehanes, Roby, Munson, Peter J., Larson, Martin G., Levy, Daniel, Ellinor, P

Journal:

Year:

2014

Language:

english

File:

PDF, 978 KB

english, 2014

26

Integrated genome-wide analysis of expression quantitative trait loci aids interpretation of genomic association studies

Joehanes, Roby, Zhang, Xiaoling, Huan, Tianxiao, Yao, Chen, Ying, Sai-xia, Nguyen, Quang Tri, Demirkale, Cumhur Yusuf, Feolo, Michael L., Sharopova, Nataliya R., Sturcke, Anne, Schäffer, Alejandro A.,

Journal:

Year:

2017

Language:

english

File:

PDF, 1.38 MB

english, 2017

27

Epigenetic Patterns in Blood Associated With Lipid Traits Predict Incident Coronary Heart Disease Events and Are Enriched for Results From Genome-Wide Association StudiesCLINICAL PERSPECTIVE

Hedman, Åsa K., Mendelson, Michael M., Marioni, Riccardo E., Gustafsson, Stefan, Joehanes, Roby, Irvin, Marguerite R., Zhi, Degui, Sandling, Johanna K., Yao, Chen, Liu, Chunyu, Liang, Liming, Huan, Ti

Journal:

Circulation Cardiovascular Genetics

Year:

2017

Language:

english

File:

PDF, 3.47 MB

english, 2017

28

Dynamic Role of trans Regulation of Gene Expression in Relation to Complex Traits

Yao, Chen, Joehanes, Roby, Johnson, Andrew D., Huan, Tianxiao, Liu, Chunyu, Freedman, Jane E., Munson, Peter J., Hill, David E., Vidal, Marc, Levy, Daniel

Journal:

The American Journal of Human Genetics

Year:

2017

Language:

english

File:

PDF, 761 KB

english, 2017

29

Epigenome-wide association of DNA methylation in whole blood with bone mineral density

Morris, John A, Tsai, Pei-Chien, Joehanes, Roby, Zheng, Jie, Trajanoska, Katerina, Soerensen, Mette, Forgetta, Vincenzo, Castillo-Fernandez, Juan Edgar, Frost, Morten, Spector, Tim D, Christensen, Kaa

Journal:

Journal of Bone and Mineral Research

Year:

2017

Language:

english

File:

PDF, 449 KB

english, 2017

30

Dynamic Role of trans Regulation of Gene Expression in Relation to Complex Traits

Yao, Chen, Joehanes, Roby, Johnson, Andrew D., Huan, Tianxiao, Liu, Chunyu, Freedman, Jane E., Munson, Peter J., Hill, David E., Vidal, Marc, Levy, Daniel

Journal:

The American Journal of Human Genetics

Year:

2017

File:

PDF, 1.01 MB

2017

31

Novel Blood Pressure Locus and Gene Discovery Using Genome-Wide Association Study and Expression Data Sets From Blood and the Kidney

Wain, Louise V., Vaez, Ahmad, Jansen, Rick, Joehanes, Roby, van der Most, Peter J., Erzurumluoglu, A. Mesut, O’Reilly, Paul F., Cabrera, Claudia P., Warren, Helen R., Rose, Lynda M., Verwoert, Germain

Journal:

Year:

2017

Language:

english

File:

PDF, 2.16 MB

english, 2017

32

MicroRNA Signature of Cigarette Smoking and Evidence for a Putative Causal Role of MicroRNAs in Smoking-Related Inflammation and Target Organ DamageCLINICAL PERSPECTIVE

Willinger, Christine M., Rong, Jian, Tanriverdi, Kahraman, Courchesne, Paul L., Huan, Tianxiao, Wasserman, Gregory A., Lin, Honghuang, Dupuis, Josée, Joehanes, Roby, Jones, Matthew R., Chen, George, B

Journal:

Circulation Cardiovascular Genetics

Year:

2017

Language:

english

File:

PDF, 848 KB

english, 2017

33

Homocysteine levels associate with subtle changes in leukocyte DNA methylation: an epigenome-wide analysis

Mandaviya, Pooja R, Aïssi, Dylan, Dekkers, Koen F, Joehanes, Roby, Kasela, Silva, Truong, Vinh, Stolk, Lisette, Heemst, Diana van, Ikram, M Arfan, Lindemans, Jan, Slagboom, P Eline, Trégouët, David-Al

Journal:

Year:

2017

Language:

english

File:

PDF, 2.08 MB

english, 2017

34

Epigenome-wide association studies identify DNA methylation associated with kidney function

Chu, Audrey Y., Tin, Adrienne, Schlosser, Pascal, Ko, Yi-An, Qiu, Chengxiang, Yao, Chen, Joehanes, Roby, Grams, Morgan E., Liang, Liming, Gluck, Caroline A., Liu, Chunyu, Coresh, Josef, Hwang, Shih-Je

Journal:

Nature Communications

Year:

2017

Language:

english

File:

PDF, 1.01 MB

english, 2017

35

Whole blood gene expression and white matter Hyperintensities

Lin, Honghuang, Satizabal, Claudia, Xie, Zhijun, Yang, Qiong, Huan, Tianxiao, Joehanes, Roby, Wen, Chengping, Munson, Peter J., Beiser, Alexa, Levy, Daniel, Seshadri, Sudha

Journal:

Molecular Neurodegeneration

Year:

2017

Language:

english

File:

PDF, 935 KB

english, 2017

36

Association of Body Mass Index with DNA Methylation and Gene Expression in Blood Cells and Relations to Cardiometabolic Disease: A Mendelian Randomization Approach

Mendelson, Michael M., Marioni, Riccardo E., Joehanes, Roby, Liu, Chunyu, Hedman, Åsa K., Aslibekyan, Stella, Demerath, Ellen W., Guan, Weihua, Zhi, Degui, Yao, Chen, Huan, Tianxiao, Willinger, Christ

Journal:

Year:

2017

Language:

english

File:

PDF, 3.64 MB

english, 2017

37

Genetically Determined Lipoprotein(a) Concentrations are Associated with Widespread Changes in Leukocyte DNA Methylation

Mendelson, Michael M., Joehanes, Roby, Huan, Tianxiao, Yao, Chen, Liu, Chunyu, Levy, Daniel, Thanassoulis, George

Journal:

Atherosclerosis Supplements

Year:

2018

Language:

english

File:

PDF, 44 KB

english, 2018

38

Genome-wide DNA methylation study of hand osteoarthritis

Yau, M.S., Joehanes, R., Hsu, Y.-H., Kiel, D.P., Felson, D.T.

Journal:

Osteoarthritis and Cartilage

Year:

2018

Language:

english

File:

PDF, 316 KB

english, 2018

39

Whole Blood Gene Expression Associated with Clinical Biological Age

Lin, Honghuang, Lunetta, Kathryn L, Zhao, Qiang, Mandaviya, Pooja R, Rong, Jian, Benjamin, Emelia J, Joehanes, Roby, Levy, Daniel, van Meurs, Joyce B J, Larson, Martin G, Murabito, Joanne M

Journal:

The Journals of Gerontology Series A Biological Sciences and Medical Sciences

Year:

2018

Language:

english

File:

PDF, 997 KB

english, 2018

40

A Peripheral Blood DNA Methylation Signature of Hepatic Fat Reveals a Potential Causal Pathway for Non-Alcoholic Fatty Liver Disease

Ma, Jiantao, Nano, Jana, Ding, Jingzhong, Zheng, Yinan, Hennein, Rachel, Liu, Chunyu, Speliotes, Elizabeth K., Huan, Tianxiao, Song, Ci, Mendelson, Michael M., Joehanes, Roby, Long, Michelle T., Liang

Journal:

Year:

2019

Language:

english

File:

PDF, 3.77 MB

english, 2019

41

0021 Lower Oxygen Saturation During Sleep Is Associated With Reduced Expressions Of Cd1d And Rab20 That Is Potentially Reversed By CPAP Therapy

Sofer, Tamar, Li, Ruitong, Joehanes, Roby, Lin, Honghuang, Gower, Adam, Punjabi, Naresh, Mehra, Reena, Patel, Sanjay, Quan, Stuart, Liu, Yongmei, Gharib, Sina, Levy, Daniel, Spira, Avrum, Redline, Sus

Journal:

Year:

2019

Language:

english

File:

PDF, 121 KB

english, 2019

42

0021 Lower Oxygen Saturation During Sleep Is Associated With Reduced Expressions Of Cd1d And Rab20 That Is Potentially Reversed By CPAP Therapy

Sofer, Tamar, Li, Ruitong, Joehanes, Roby, Lin, Honghuang, Gower, Adam, Punjabi, Naresh, Mehra, Reena, Patel, Sanjay, Quan, Stuart, Liu, Yongmei, Gharib, Sina, Levy, Daniel, Spira, Avrum, Redline, Sus

Journal:

Year:

2019

File:

PDF, 121 KB

2019

43

Association of dietary folate and vitamin B-12 intake with genome-wide DNA methylation in blood: a large-scale epigenome-wide association analysis in 5841 individuals

Mandaviya, Pooja R, Joehanes, Roby, Brody, Jennifer, Castillo-Fernandez, Juan E, Dekkers, Koen F, Do, Anh N, Graff, Mariaelisa, Hänninen, Ismo K, Tanaka, Toshiko, de Jonge, Ester A L, Kiefte-de Jong,

Journal:

American Journal of Clinical Nutrition

Year:

2019

Language:

english

File:

PDF, 3.02 MB

english, 2019

44

Epigenome-wide association study of DNA methylation and microRNA expression highlights novel pathways for human complex traits

Huan, Tianxiao, Mendelson, Michael, Joehanes, Roby, Yao, Chen, Liu, Chunyu, Song, Ci, Bhattacharya, Anindya, Rong, Jian, Tanriverdi, Kahraman, Keefe, Joshua, Murabito, Joanne M., Courchesne, Paul, Lar

Journal:

Year:

2019

Language:

english

File:

PDF, 2.87 MB

english, 2019

45

Reference Module in Biomedical Sciences || OBSOLETE: Transcriptome and Epigenome Applications for Coronary Heart Disease Research

Year:

2018

File:

PDF, 22 KB

2018

46

Genome-wide identification of DNA methylation QTLs in whole blood highlights pathways for cardiovascular disease

Huan, Tianxiao, Joehanes, Roby, Song, Ci, Peng, Fen, Guo, Yichen, Mendelson, Michael, Yao, Chen, Liu, Chunyu, Ma, Jiantao, Richard, Melissa, Agha, Golareh, Guan, Weihua, Almli, Lynn M., Conneely, Kare

Journal:

Nature Communications

Year:

2019

Language:

english

File:

PDF, 1.67 MB

english, 2019

47

Comparison of smoking-related DNA methylation between newborns from prenatal exposure and adults from personal smoking

Sikdar, Sinjini, Joehanes, Roby, Joubert, Bonnie R, Xu, Cheng-Jian, Vives-Usano, Marta, Rezwan, Faisal I, Felix, Janine F, Ward, James M, Guan, Weihua, Richmond, Rebecca C, Brody, Jennifer A, Küpers,

Journal:

Year:

2019

Language:

english

File:

PDF, 850 KB

english, 2019

48

Association between sleep disordered breathing and epigenetic age acceleration: Evidence from the Multi-Ethnic Study of Atherosclerosis

Li, Xiaoyu, Joehanes, Roby, Hoeschele, Ina, Rich, Stephen S., Rotter, Jerome I., Levy, Daniel, Liu, Yongmei, Redline, Susan, Sofer, Tamar

Journal:

Year:

2019

File:

PDF, 418 KB

2019

49

Comparison of smoking related DNA methylation in newborns from maternal smoking exposure in pregnancy, and in adults from personal smoking

S, Sikdar, R, Joehanes, B, Joubert, S, London

Journal:

Environmental Epidemiology

Year:

2019

File:

PDF, 73 KB

2019

50

Whole Blood DNA Methylation Signatures of Diet Are Associated with Cardiovascular Disease Risk Factors and All-cause Mortality

Ma, Jiantao, Rebholz, Casey M., Braun, Kim V.E., Reynolds, Lindsay M., Aslibekyan, Stella, Xia, Rui, Biligowda, Niranjan G., Huan, Tianxiao, Liu, Chunyu, Mendelson, Michael M., Joehanes, Roby, Hu, Emi

Journal:

Circulation: Genomic and Precision Medicine

Year:

2020

File:

PDF, 874 KB

2020